Find hotels in De Soto, MO from $63

These De Soto insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: September 17, 2026.

Top reasons to visit De Soto

• Outdoor Adventures: De Soto is a paradise for outdoor enthusiasts, featuring picturesque lakes and lush parks perfect for hiking and picnicking.
• Arcade Adventure Zone: Experience the thrill of the arcade adventure zone, offering fun for all ages.
• Family-Friendly Amusement Park: Enjoy a day at the local amusement park, packed with rides and attractions for the whole family.
• Charming Neighborhoods: Explore friendly neighborhoods filled with trendy shops and dining options, showcasing local culture.
• Diverse Accommodations: Find a variety of hotels, from pet-friendly motels to family-oriented stays, ensuring comfort for every traveler.

Find great hotels near De Soto

De Soto, Missouri, offers a variety of hotel accommodations perfect for every type of traveler. From pet-friendly motels to family-oriented hotels, you're sure to find the ideal place to stay. Whether you're on a business trip or enjoying a family vacation, the local hotels provide essential services and comfort. Explore the best options in De Soto for a memorable stay, including top-rated star hotels that cater to your needs.

• WoodSpring Suites St. Louis Arnold: WoodSpring Suites St. Louis Arnold is a budget-friendly hotel located 22 miles from De Soto, ideal for business travelers and pet owners. This property features a practical and comfortable atmosphere, perfect for those seeking an extended stay. Amenities include pet-friendly accommodations with specific policies for dogs, including weight restrictions and applicable fees. Guests can enjoy fully equipped kitchens in select rooms, ensuring a home-like experience while traveling. With its focus on affordability and convenience, this hotel is a smart choice for budget-conscious visitors.
• Comfort Inn Festus - St Louis South: Comfort Inn Festus - St Louis South, situated 9 miles from De Soto, offers a welcoming environment tailored for families and business travelers alike. This budget-friendly hotel emphasizes comfort and convenience, featuring complimentary amenities such as free cribs for younger guests. The hotel’s location provides easy access to local attractions, making it a great base for exploring the area. Visitors appreciate the friendly staff and comfortable accommodations, ensuring a pleasant stay for all types of travelers.
• La Quinta Inn & Suites by Wyndham Festus - St. Louis South: La Quinta Inn & Suites by Wyndham Festus - St. Louis South is a budget-friendly hotel located 10 miles from De Soto, boasting a guest rating of 8.0 out of 10. With a focus on both business and pet-friendly travel, this property welcomes dogs and cats with specific amenities tailored to furry companions. Guests enjoy comfortable rooms and a range of services that enhance their stay, including a complimentary breakfast and a fitness center. This hotel is perfect for those looking for a blend of comfort and convenience during their visit.

Where to stay in and around De Soto

De Soto, Missouri, is a hidden gem for outdoor enthusiasts and families seeking adventure and scenic beauty. Explore the lush landscapes of local parks, perfect for hiking and picnicking, or take a leisurely stroll through family-friendly neighborhoods. Nearby, you can discover charming towns filled with friendly locals, trendy shops, and luxurious dining options, making De Soto an ideal base for excursions and memorable experiences in the heart of the Midwest.

• Festus: Located a mere 10 miles from De Soto, Festus is a vibrant city known for its outdoor activities and family-friendly atmosphere. Visitors can enjoy a variety of experiences, from exploring recreational areas to indulging in fun at the arcade adventure zone and amusement parks. The peak travel months of April and July to August make it an ideal time for families and couples looking for a romantic getaway. Notable nearby landmarks include an event conference venue and a national state park, perfect for those seeking adventure in nature.
• Hillsboro: Just 6 miles from De Soto, Hillsboro offers a charming blend of outdoor excitement and entertainment. This city attracts moderate seasonal travelers, peaking in April and June to July. Visitors can enjoy skiing and other recreational activities, making it a popular choice for couples and adventure seekers. The proximity to a national state park and local lakes enhances the area's appeal, providing ample opportunities for exploration and relaxation amidst stunning natural scenery.
• Olympian Village: Nestled within the De Soto area, Olympian Village is a quaint village that provides a delightful escape for those seeking outdoor and romantic experiences. With peak travel times in February and June to July, this area offers a range of activities such as golfing and enjoying recreational areas. Visitors can also explore nearby lakes and urban parks, making it a great spot for relaxation and leisure. Olympian Village is perfect for those wanting to unwind while enjoying the beauty of nature.

Things to do in De Soto

De Soto offers a perfect getaway for outdoor enthusiasts and adventurers. Visitors can enjoy a variety of activities, including exploring the recreational area, experiencing the thrill of the arcade adventure zone, and having fun at the amusement park. With its scenic views and engaging attractions, De Soto is an ideal destination for those looking to embrace nature and excitement.

Shopping

De Soto offers charming local shops perfect for finding unique gifts and souvenirs. For a larger selection, visit the Festus Marketplace, just 10 miles away, featuring a variety of retail options. If you're up for a drive, explore the Jefferson County Mall, located 15 miles away, with diverse shopping experiences.

Recreation

Serenity Spa in De Soto offers rejuvenating treatments, from massages to facials, promoting relaxation and wellness. For outdoor fun, visit the beautiful De Soto City Park, where you can hike scenic trails, enjoy picnics, and partake in recreational sports surrounded by nature's tranquility.

Adventure

Explore the scenic trails at Huzzah Conservation Area, perfect for hiking and mountain biking amidst stunning landscapes. For a thrilling experience, try canoeing or kayaking on the nearby Meramec River, where you can enjoy wildlife and beautiful views while navigating the gentle currents.

Nightlife

De Soto’s nightlife offers a cozy atmosphere with local bars like the Old Town Tavern, perfect for drinks and live music. For a lively vibe, check out the De Soto Eagles for social events and entertainment. Enjoy a relaxed evening mingling with friendly locals.

Booking tips and Expedia advantages for De Soto

• The most and least expensive months on average to stay in a hotel: The cheapest months to stay in De Soto are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
• The most and least expensive days on average to stay in a hotel: The least expensive day to stay in De Soto is Monday. The most expensive day to stay in De Soto is Saturday.
• Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences such as budget, desired location, and hotel type. For instance, selecting the Eco-certified filter will showcase available sustainable and eco-friendly hotels. To find the best prices and deals, simply sort the price filter from low to high.
• Consider bundling your trip: You can save money by combining your De Soto hotel reservations with your flights and activities through an Expedia package.

Find the best attractions near De Soto

De Soto, Missouri, is perfect for outdoor enthusiasts seeking adventure and scenic beauty. Visitors can enjoy a variety of attractions, including picturesque lakes, lush parks, and national or state parks. Whether you're looking for a beach experience or just want to soak in nature, De Soto offers a range of points of interest that cater to all outdoor lovers.

• Washington State Park: Located 9 miles from De Soto, this beautiful national park offers breathtaking scenery and numerous outdoor adventures. Hike along scenic trails, explore picturesque landscapes, and enjoy a relaxing day surrounded by nature.
• Sandy Creek Covered Bridge State Historic Site: Situated 11 miles away, this modern bridge features charming city vibes while showcasing historical architecture. It's a great spot for photography and a leisurely stroll, immersing yourself in the area's rich history.
• St. Francois State Park: Also 11 miles from De Soto, this national park is known for its stunning natural beauty and outdoor activities. Enjoy hiking, fishing, and picnicking in a serene environment perfect for wildlife enthusiasts.

Best time to go to De Soto

The best time to visit De Soto is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	32.5°F (0.3°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly Low
February	35.6°F (2.0°C)	Light Rain	Mostly Sunny	Average	Slightly Low
March	46.6°F (8.1°C)	Light Rain	Mostly Sunny	Average	Average
April	55.9°F (13.3°C)	Light Rain	Mostly Sunny	Average	Average
May	65.7°F (18.7°C)	Light Rain	Mostly Sunny	Average	Slightly High
June	75.4°F (24.1°C)	Light Rain	Mostly Sunny	Moderately High	Slightly High
July	78.4°F (25.8°C)	Light Rain	Mostly Sunny	Moderately High	Slightly High
August	76.5°F (24.7°C)	Light Rain	Mostly Sunny	Moderately High	Average
September	70.0°F (21.1°C)	Light Rain	Mostly Sunny	Average	Average
October	58.1°F (14.5°C)	Light Rain	Mostly Sunny	Moderately Low	Average
November	46.0°F (7.8°C)	Light Rain	Mostly Sunny	Average	Average
December	38.1°F (3.4°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly Low

The nearest major airports for your trip to De Soto

For your trip to De Soto, Missouri, the major airport to consider is St. Louis Lambert International Airport (STL), located 43 miles away. Nearby accommodations include The Ritz-Carlton, St. Louis, and Ameristar Casino Resort and Spa, each just 7 miles from the airport. Another option is the Royal Sonesta Chase Park Plaza, situated 9 miles from STL. If you're considering Fort Leonard Wood Regional Airport (TBN), it’s 91 miles from De Soto, with options like Z Loft Extended Stay Hotel and Baymont Inn and Suites nearby. Cape Girardeau Municipal Airport (CGI) is 83 miles away, offering hotels such as Drury Plaza Hotel and Courtyard by Marriott for your convenience.